Bibliografie

(eng): With great concern, we read the manuscript “Does the healthy vaccinee bias rule them all?” by Furst et al. The existence of a potential bias in the characteristics of target populations in observational studies is routinely considered in studies addressing vaccine effectivity. However, the claims by Furst et al. are not substan-tiated by any valid statistical analysis and are based primarily on speculation. The authors rely on simple descriptive statistics and do not provide any valid statistical quantification of individual contributing factors or comorbidity analysis of target populations. Importantly, the study does not include any information on COVID-19 infections or COVID-19-related deaths in study cohorts. Without this critical information, the conclusions of the presented study are speculative and unsubstantiated.